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Niacin and Niacinamide: Understanding the Difference

Niacin and Niacinamide: Understanding the Difference

Posted on Feb 22, 2024 at 6:32 PM

Are you curious about the difference between niacin and niacinamide? These two forms of vitamin B3 are often used interchangeably, but they have distinct properties and benefits. Let's delve into the details:

Niacin (Nicotinic Acid):

  • Benefits: Niacin is essential for overall health, supporting functions such as energy metabolism, nervous system health, and cardiovascular health. It helps convert food into energy and plays a role in DNA repair.

  • Side Effects: Niacin can cause flushing, itching, and tingling sensations, especially in high doses. This flushing effect is due to vasodilation, where blood vessels widen, leading to redness and warmth in the face and neck.

Niacinamide (Nicotinamide):

  • Benefits: Niacinamide is another form of vitamin B3 with similar benefits to niacin. It supports skin health, aids in reducing inflammation, and may help treat acne and other skin conditions. Additionally, niacinamide does not typically cause flushing, making it more tolerable for some individuals.

  • Side Effects: Niacinamideis generally well-tolerated and does not usually cause flushing or other adverse reactions, even at higher doses.

Understanding the differences between niacin and niacinamide can help you choose the right form of vitamin B3 for your specific needs. Whether you're looking to support overall health or improve skin health, both forms offer valuable benefits without significant side effects.

Research and References:

Niacin (Nicotinic Acid):

  • Alberts, A. W. (1980). Discovery, biochemistry and biology of lovastatin. The American journal of cardiology, 62(15), 10J-15J. PMID: 6150066

  • Kamanna, V. S., & Kashyap, M. L. (2008). Mechanism of action of niacin. The American journal of cardiology, 101(8), 20B-26B. PMID: 18375218

Niacinamide (Nicotinamide):

  • Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of cosmetic dermatology, 3(2), 88-93. PMID: 17147561

  • Bissett, D. L., Oblong, J. E., & Berge, C. A. (2005). Niacinamide: A B vitamin that improves aging facial skin appearance. Dermatologic surgery, 31, 860-865. PMID: 16029679

These studies provide insights into the mechanisms of action, benefits, and potential side effects of niacin and niacinamide, which can be helpful in understanding their differences and choosing the appropriate form for specific health or skincare needs.